Trichopol and alcohol
"Trichopol" is now widely used as amedicinal antibacterial preparation. To treat intestinal infections, giardiasis, gingivitis, trichomoniasis, trichopolis is used. Description of the drug contains a list of its pharmacological properties. The restored nitro group of metronidazole (trichopole) interacting with the DNA of the causative agent cell of the infection, inhibits their synthetic activity and leads to the death of the microorganism. In recent years, this drug has proven itself in the treatment of alcoholism.
What is the basis for the use of the drug Trichopol? "Trichopol" and alcohol when interacting with each other lead to the development of an allergic reaction. Running the mechanism of blocking the enzymatic system responsible for the destruction of substances, leads to the fact that the body accumulates the products of alcohol destruction. These substances can cause pain in the abdominal region, nausea, vomiting and redness of the skin. Developing when drinking alcohol, the reaction is called disulfiram-ethanol. The blocking of the enzyme acetaldehyde dehydrogenase of the human body leads to the formation and accumulation of intermediate (incomplete) decomposition product of ethanol - acetic aldehyde. Being a poison for a person, the latter leads to the development of acute intoxication.
The drug "Trichopol" and alcohol cause an increasein the blood level of acetaldehyde, which is the initiator of pain and other sensations. The use of this drug also causes an increase in heart rate and a decrease in the level of blood pressure. Psychological fixation of alcohol intolerance is absorbed by patients, which in the future prevents its use. The rapidly evolving reaction continues for a long time. Manifestations of intoxication are eliminated within eight to twelve hours. Duration of complete removal of the drug from the body is two days.
Assigning the drug "Trichopol" for the purpose of treatmenttrichomoniasis, the doctor necessarily warns the patient about the consequences of using the combination of "trichopolum and alcohol", since the consequences of developing allergic reactions are often unpredictable.
Developing allergic reaction may manifest as Quincke's edema, profuse rashes on the skin, dyspepsia, diarrhea, dryness in the mouth and metal taste.
Trichopol and alcohol, when used together, can cause severe headache and blurred consciousness in patients with neurological disorders.
In order to ensure safe usethe drug is prescribed by a doctor. Before using a pharmaceutical preparation, it is highly recommended to study the instruction with a description of the properties and characteristics of the drug.
To treat peptic ulcer, the drug "Trichopol" is also used. Indications for use include amoeba liver damage, as well as pathology of the pelvic organs.
Thus, the application of "Trichopol" todayis very common, both as an antibacterial drug (for the treatment and prevention of infectious pathology), and as a means to form a conditioned reflex connection, to eliminate addiction to alcohol. However, at present many microorganisms have developed resistance to this antibacterial agent, so its effectiveness in this regard has significantly decreased. The purpose of this drug is justified in a number of cases in the treatment of infections caused by microorganisms that are sensitive to tricholum, for example, in peptic ulcer associated with Helicobacter pylori infection.
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