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The best antihistamines are 4 generations

About what are antihistaminesdrugs are best known to people who suffer from allergies from time to time. Sometimes only a timely medication can save them from painfully itchy rashes, severe coughing, swelling and redness. Antihistamines of 4 generations are modern means that affect the body instantly. In addition, they are quite effective. The result from them persists for a long time.

antihistamines 4 generations

Effects on the body

To understand the difference between antihistamines of 4 generations, it is necessary to understand the mechanism of action of antiallergic drugs.

These drugs block the H1- andH2-histamine receptors. This helps reduce the reaction of the body with histamine mediator. Thus, the allergic reaction stops. In addition, these funds serve as an excellent prophylaxis of bronchospasm.

Consider antihistamines of all generations. This will allow us to understand the advantages of modern means.

First Generation Medicines

This category includes sedatives. They block H1-receptors. The duration of these drugs is 4-5 hours. The drugs have a good anti-allergic effect, but they have a number of drawbacks, among which:

  • dilated pupil;
  • dryness in the oral cavity;
  • blurred vision;
  • drowsiness;
  • decrease in tone.

Common drugs of the first generation are:

  • "Dimedrol";
  • "Diazolin";
  • "Tavegil";
  • Suprastin;
  • "Peritol";
  • "Pipolphen";
  • Fenkarol.

best antihistamines 4 generations

These drugs are usually prescribed to people,suffering from chronic diseases, in which there is difficulty breathing (bronchial asthma). In addition, they will have a beneficial effect in an acute allergic reaction.

Preparations of the 2nd generation

These drugs are called non-sedative. Such means no longer have an impressive list of side effects. They do not provoke drowsiness, a decrease in brain activity. In case of allergic rashes and itching of the skin, medicines are in demand.

The most popular drugs are:

  • "Claritin";
  • "Treksil";
  • "Zodak";
  • Fenistil;
  • "Histalong";
  • Semprex.

However, a major drawback of these drugs is the cardiotoxic effect. That is why these funds are banned for consumption by people suffering from cardiovascular pathologies.

Medicines of the 3rd generation

These are active metabolites. They have excellent anti-allergic properties and are characterized by a minimal list of contraindications. If we talk about effective antiallergic drugs, then these drugs just represent modern antihistamines.

antihistamines 4 generations list

What are the most popular drugs in this group? These are the following medicines:

  • Zirtek;
  • "Cetrin";
  • "Telfast".

They do not have a cardiotoxic effect. Often they are prescribed for acute allergic reaction and asthma. Excellent results they provide in the fight against many dermatological diseases.

Preparations of the 4th generation

Recently, specialists invented the latestmedicines. These are antihistamines of 4 generations. They are characterized by the rapidity of action and the long-lasting effect. Such drugs perfectly block H1-receptors, eliminating all the undesirable symptoms of allergies.

The great advantage of such medications is that their use does not harm the functioning of the heart. This allows us to consider them safe enough.

However, one should not forget that they havecontraindications. Such a list is rather small, mainly it is a child's age and pregnancy. But still it is recommended to consult a doctor before use. It is not superfluous to study the instruction in detail before using antihistamines of the 4th generation.

The list of such medicines is as follows:

  • "Levocetirizine";
  • "Erius";
  • Desloratadine;
  • "Ebastin";
  • "Fexofenadine";
  • Bamipin;
  • Fenspiride;
  • "Cetirizine";
  • Xizal.

modern antihistamines for 4 generations

The best drugs

It is quite difficult to distinguish from the drugs of the 4thGenerations are the most effective. Since such drugs were developed not so long ago, there are few newer antiallergic agents. In addition, all preparations are good in their own way. Therefore, it is not possible to isolate the best antihistamines of the 4th generation.

The drugs containingphenoxofenadine. Such drugs do not have a hypnotic and cardiotoxic effect on the body. These funds today rightfully occupy the place of the most effective antiallergic medicines.

Derivatives of cetirizine are often used to treat skin manifestations. After eating 1 tablet, the result is noticeable after 2 hours. In this case, it remains for a fairly long time.

The active metabolite of the known "Loratadin" is the medicine "Erius". This drug is about 2.5 times effective than its predecessor.

The drug "Xizal" deserved great popularity.It perfectly blocks the release of inflammatory mediators. As a result of this effect, this remedy reliably eliminates allergic reactions.

The medicine "Cetirizin"

This is quite an effective tool. Like all modern antihistamines of 4 generations, the medicine in the body is practically not metabolized.

antihistamines 4 generations of medicine

The drug proved to be highly effectivewith skin rashes, as it is able to penetrate perfectly into the integument of the epidermis. Long-term use of this drug in infants suffering from early atopic syndrome significantly reduces the risk of progression of such conditions in the future.

2 hours after taking the tablet comesnecessary proof effect. Since it persists for a long time, it is enough to take 1 pill a day. Some patients to take the necessary result can take 1 tablet every other day or twice a week.

The drug has a minimal sedative effect. However, patients suffering from kidney pathologies should use this remedy extremely cautiously.

The drug in the form of a suspension or syrup is allowed to use crumbs from two years.

The medicine "Fexofenadine"

This agent is a metabolite of terfenadine.Such a drug is known and called "Telfast". Like other antihistamines of the 4th generation, it does not provoke drowsiness, it is not metabolized and does not affect psychomotor functions.

This tool is one of the safest, butwith extremely effective drugs among all antiallergic medicines. The drug is in demand for all manifestations of allergies. Therefore, doctors prescribe it for almost all diagnoses.

Anti-histamine tablets "Fexofenadine" are prohibited for admission to children under the age of 6 years.

modern antihistamines which drugs

The drug Desloratadine

This medicine also belongs to popularantiallergic agents. It can be used for any age groups. As pharmacologists have been proven to be highly safe, such a remedy is dispensed in pharmacies without a prescription.

The drug has a small sedative effect, nothas a harmful effect on cardiac activity, does not affect the psychomotor sphere. Often, the medicine is well tolerated by patients. In addition, it does not interact with other medications.

One of the most effective medicines from thisgroup is considered the drug "Erius". This is a powerful antiallergic medicine. However, during pregnancy it is contraindicated. In the form of syrup, a medicine is allowed to take infants from 1 year of age.

The drug "Levocetirizine"

This tool is better known as"Suprastinex", "Tsezer". This is an excellent drug, which is prescribed for patients suffering from an allergic reaction to pollen. The agent is prescribed in case of seasonal manifestations or all-the-year-round. The drug is in demand for the treatment of conjunctivitis, allergic rhinitis.

antihistamines of all generations

It is recommended to take the medicine in the morning or during a meal. The drug should not be combined with alcohol.


Medicines of the new generation are activemetabolites of previously used drugs. Undoubtedly, this property makes antihistamines of the 4th generation extremely effective. Medicines in the human body are not metabolized, but they give a long and pronounced result. In contrast to the means of previous generations, such drugs do not have a harmful effect on the liver.

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