Ointment Sinaflan - recommendations for use
Ointment Sinaflan belongs to the group of topicalglucocorticosteroids. The main active substance in this preparation is fluocinolone acetonide. This substance is obtained in a synthetic way, it has pharmacological activity, which is similar to glucocorticosteroids. Ointment Sinaphlan, more precisely, each of its molecules, in its composition has two additional fluorine atoms, due to this there is a decrease in local absorption and its anti-inflammatory effect is enhanced. The main active substance of this drug has a high glucocorticoid activity and almost no mineralocorticoid action. With topical application, Ointment Sinaphlan has antiallergic, antipruritic and anti-inflammatory effects, in addition, this drug activates local vasodilation.
The action of this drugmeans there is a process of inhibition of phospholipase A2. The activity of this enzyme is suppressed and, thus, the conversion of arachidonic acid to its pharmacologically active form is prevented. Due to this effect, the number of leukotrienes and prostaglandins decreases, which are the main mediators of inflammation.
Due to the fact that the release is reducedhistamine, ointment Sinaphlan causes oppression of the development of the hypersensitivity reaction. After using Sinaflana, the risk of the emergence and development of exudative reactions is significantly reduced, because the lumen of the vessels is narrowing. Also, this drug reduces the synthesis of protein and collagen deposits.
Ointment is applied topically, it penetrates wellthrough the stratum corneum of the epidermis and accumulates in the dermis. This drug is not biotransformed in the skin. It should be noted that systemic absorption in adolescents and children is significantly higher than in adults.
Sinaflana Ointment - instructions for use
The use of the drug is recommended for various skin ailments, when it is necessary to conduct therapy with glucocorticosteroids. These are the diseases:
- discoid lupus erythematosus and lichen planus;
- psoriasis and seborrhea of the skin;
- the presence of varying degrees of eczematous lesions;
- neurodermatitis and allergic skin reactions, as well as skin itching;
- occurrence of burns of the first degree, including sunburn;
- bites of various insects.
Ointment Sinaflana (instructions for usethis drug is fairly simple) is applied to the affected areas up to 3 times a day. It should be remembered that after applying the ointment, it should be rubbed into the sore spot. Treatment with this drug is carried out for 5-10 days, but in cases of need it can be continued for up to 25 days. Applying ointment to sensitive and large areas of the skin is not recommended.
Possible side effects
If the ointment is used for a long timetime, patients may experience skin atrophy and even develop necrosis. If applied to large or sensitive areas of the skin, then hypofunction of the adrenal gland may appear.
Contraindications to the use of the drug:
- the patient has an increased individual sensitivity to the components of the drug;
- with infectious diseases of the skin of various etiologies;
- Do not apply ointment on skin areas where there are ulcerative lesions, and you can not apply ointment to open wounds;
- The use of this drug during pregnancy and skin tuberculosis is prohibited.
Since this medication is applied topically, its overdose is not possible.
Keep Sinaflana Ointment away from direct sunlight, in a dry room and the ambient temperature should not exceed 30 degrees.
Remember that the use of this drug should be preceded by a consultation with a doctor.</ p>>